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Targeting estrogen to the brain via DHED does not seem to protect against metabolic dysfunction in obese OVX mice

Posted by Celine Camon on 1 September 2026

Tags: dihydroxyestra-1, 4-dien-3-one, DHED, estrogen, menopause, metabolic health, hypothalamus

Camon C, Kip E, Lord R, Decourt C, Prescott M, Clarkson J, Sandoval N, Vander P, van Veen J, Prokai-Tatrai K, Correa S, Campbell R, Garratt M. 2026. Targeting estrogen to the brain via DHED does not seem to protect against metabolic dysfunction in obese OVX mice. Endocrinology. doi: 10.1210/endocr/bqag082

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